Inside are the Vatican palace and gardens, St. Peter’s Basilica, and St. Peter’s Square, an area ruled by the Pope, supreme head of the Roman Catholic Church. This compact space offers a lot of things to see, between its museums and the great basilica itself.

Inside St. Peter’s Basilica is Michelangelo’s masterpiece, Pieta, along with statuary and altars by Bernini and others. The unquestioned highlight of the Vatican museums is the Sistine Chapel, whose magnificent frescoed ceiling is Michelangelo’s most famous work.

In the Vatican Palace are the Raphael Rooms; the Borgia Apartments; the Vatican Library, and a number of museums that include the Picture Gallery, Museum of Secular Art, Etruscan Museum, and others. The collections you can see in these cover everything from papal coaches to 20th-century art reflecting religious themes.

Ticket lines for the Vatican’s top attractions are incredibly long, and you can spend several hours waiting in line.

To save time, purchase a Skip the Line: Vatican Museums with St. Peter’s, Sistine Chapel, and Small-Group Upgrade tour in advance. This three-hour tour allows you to bypass the long lines and walk straight into the museums with a knowledgeable guide. Headsets are provided, and you can choose from several different departure times or upgrade to an evening or small-group tour.